Pain in the upper abdomen or back

This nonspecific symptom commonly occurs with pancreatic cancer and may worsen when lying down or 3 to 4 hours after eating. Large tumours that press against nearby organs can cause pain. Pain can also result if the tumour blocks the digestive tract.  

Jaundice

Jaundice is a condition marked by yellowing of the skin and eyes, dark urine, and light-coloured or greasy stools. Jaundice is the result of a tumour completely or partially blocking the bile duct, slowing the flow of bile into the small intestine. This leads to an increased level of bilirubin, a liver byproduct secreted in bile, in the blood.

Changes in stool colour

Stools become pale and clay in colour. This is often due to blockage of the bile duct. Stools can also have an odd, strong smell or float if they have too high fat content.

Loss of appetite and unintended weight loss

Cancer-induced weight loss is a complex problem that affects the way the body uses calories and protein. Cancer can cause the body to burn more calories than usual, break down muscle and decrease appetite. A person may also notice a change in appetite or desire for certain foods. 

Diabetes

Diabetes is a condition in which the body does not make, or properly use insulin. Insulin helps the body use glucose (sugar) efficiently. Research suggests that a sudden onset of type 2 diabetes in people age 50 or older may be an early symptom of pancreatic cancer, especially in those who have a low body mass index (BMI), experience continuous weight loss or do not have a family history of diabetes. A sudden change in blood sugar levels in diabetics who previously had well-controlled diabetes may also be a sign of pancreatic cancer.

Nausea and vomiting/digestive issues

Nausea, indigestion and poor appetite are common symptoms in people with pancreatic cancer. Digestive issues can be caused by the tumour pressing against digestive organs or blockages of the pancreatic duct. 

Fatigue

The definition of fatigue is extreme tiredness. Severe fatigue can make it difficult to get up in the morning and make it through the day. Many conditions and lifestyle factors can cause fatigue, which is why this symptom is often overlooked.

Overall skin itch

This is a less common and a vague symptom that is usually coupled with other symptoms like abdominal pain or jaundice. 

Diarrhea and constipation

When the nutrients in food are not absorbed properly, you may experience diarrhea. This can cause a loose stool that is watery, oily, and foul-smelling. Constipation is a common problem, particularly in patients taking pain medications. These medications slow the passage of food through the intestines.